Vitamin B1 and bacterial oxidations

Vitamin B1

Vitamin B1 is a watersoluble vitamin. It consists out of a pyrimidineand a thiazol ring, which are synthesized independently and linked afterwards.Vitamin B1 is de novo produced by many plants and microorganisms. Humans and animals have to take it up by nutrition. They are only able to do the phosphorylation reaction of the thiamin molecule. Thiamin is found free and as mono-, diand triphosphat...

Intestinal Flora and Vitamin B1

Vitamin-B1 Deficiency

Vitamin B1 Deficient Animals and Poliomyelitis *

In previous experiments,2 an unsuccessful attempt was made to acclimate monkey cord virus to white rats, which had been made completely vitamin B1 deficient by feeding them a vitamin B1 free diet for 30 days prior to the start of the experiment. It was thought that our failure might have been due to the fact that we did not have the animals in a proper state or stage of deficiency; perhaps the ...

Effects of thyroxine and some related compounds on bacterial oxidations.

It was recently observed in our laboratory that the oxidation of cholesterol in vitro by intestinal bacteria is stimulated by 2,4-dinitrophenol (1). In preliminary experiments with the same bacterial system, L-thyroxine was also found to accelerate the oxidation of cholesterol and of glucose (2). The work to be described here includes an extension of these studies and, in addition, results obta...